January 1, 1999Journal of Neuroimaging
Intima‐media Thickness of Carotid Arteries in Borderline Hypertensives
Key result
Higher BMI (29.2 vs 26.5 kg/m2) and lower HDL-cholesterol (1.1 vs 1.42 mmol/l) were significantly associated with the highest versus lowest tertile of carotid intima-media thickness (p<0.025).
Population
48 subjects originally borderline hypertensives, mean age 61.9 +/- 2.54 years
Design
Cross-sectional
Authors
Discussion
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Implication
Supports metabolic screening in borderline hypertension; leaves open causal role of BMI/HDL in carotid atherosclerosis progression.
Study Design
Type
Cross-Sectional (n=48)
Structured PICO
P
Population
48 originally borderline hypertensive subjects (mean age 61.9 years) evaluated for cardiovascular risk factors and carotid intima-media thickness.
O
Outcome
Far wall common carotid artery intima-media thickness (IMT CCA) measured by B-mode ultrasoundsurrogate
Main Result
p-value: p=<0.025
Higher BMI and lower HDL-cholesterol are associated with increased carotid intima-media thickness in borderline hypertensive patients.
Cite This Study
Piťha et al. (1999) conducted a cross-sectional in Borderline hypertension (n=48). Cardiovascular risk factors (BMI, HDL-cholesterol) vs. First vs third tertile of IMT CCA was evaluated on Intima-media thickness of common carotid artery (IMT CCA) (p=<0.025). Higher BMI (29.2 vs 26.5 kg/m2) and lower HDL-cholesterol (1.1 vs 1.42 mmol/l) were significantly associated with the highest versus lowest tertile of carotid intima-media thickness (p<0.025).