Key result
Betatrophin concentrations of 300-600 pg/mL and >600 pg/mL were independently associated with a higher risk of gestational diabetes mellitus compared to concentrations <300 pg/mL.
Why the study?
Does betatrophin concentration predict the risk of gestational diabetes mellitus and postpartum type 2 diabetes mellitus in pregnant patients?
Population
386 pregnant patients evaluated for gestational diabetes mellitus and postpartum type 2 diabetes mellitus
Comparison
Betatrophin concentration assessment vs Patients with lower betatrophin concentrations…
Design
Cohort
Authors
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May inform GDM risk stratification in pregnancy; hypothesis-generating and requires prospective validation before clinical use.
Observational (n=386)
Does betatrophin concentration predict the risk of gestational diabetes mellitus and postpartum type 2 diabetes mellitus in pregnant patients?
Betatrophin may serve as a sensitive diagnostic marker for gestational diabetes and a promising predictor for postpartum type 2 diabetes.
Pan et al. (2018) conducted an observational in Gestational diabetes mellitus (n=386). Betatrophin concentration vs. Betatrophin concentration <300 pg/mL was evaluated on Risk of gestational diabetes mellitus and postpartum type 2 diabetes. Betatrophin concentrations of 300-600 pg/mL and >600 pg/mL were independently associated with a higher risk of gestational diabetes mellitus compared to concentrations <300 pg/mL.
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