Key result
Pregnant women with normal glucose regulation had almost 4 times higher betatrophin levels than unpregnant women, which were positively associated with beta cell function and lipid levels.
Population
80 women, comprising 49 pregnant women and 31 age-matched unpregnant women with normal glucose regulation.
Design
Cross-sectional
Authors
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Should not change gestational metabolic assessment; hypothesis-generating for betatrophin in beta-cell adaptation.
Cross-Sectional (n=80)
Pregnancy is associated with significantly increased betatrophin levels, which correlate with beta cell function and lipid levels.
Huang et al. (2016) conducted a cross-sectional in Pregnancy and Gestational Diabetes Mellitus (n=80). Pregnancy vs. Unpregnant women with normal glucose regulation was evaluated on Betatrophin levels and association with beta cell function. Pregnant women with normal glucose regulation had almost 4 times higher betatrophin levels than unpregnant women, which were positively associated with beta cell function and lipid levels.
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