Key result
Pregnant women with gestational diabetes mellitus had significantly higher serum betatrophin levels compared to normoglycemic controls (p<0.001), which correlated with insulin resistance.
Why the study?
The role of betatrophin in the etiopathogenesis of gestational diabetes mellitus and its association with lipid and carbohydrate metabolism remained to be investigated.
Population
60 pregnant women (30 with GDM and 30 matched healthy controls)
Comparison
Pregnant women with GDM vs matched healthy normoglycemic pregnant women
Authors
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Higher betatrophin in GDM may mark insulin resistance; observational data leaves open diagnostic or therapeutic utility.
Case-Control (n=60)
p-value: p=<0.001
Serum betatrophin levels are significantly elevated in pregnant women with GDM and correlate with insulin resistance parameters.
Bulmuş et al. (2020) conducted a case-control in Gestational diabetes mellitus (n=60). Gestational diabetes mellitus vs. Normoglycemic pregnant women was evaluated on Serum betatrophin levels (p=<0.001). Pregnant women with gestational diabetes mellitus had significantly higher serum betatrophin levels compared to normoglycemic controls (p<0.001), which correlated with insulin resistance.
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