Key result
Women with gestational diabetes mellitus had significantly higher median serum betatrophin levels compared to healthy pregnant controls (1.79 vs 1.58 μg/l; P=0.002).
Why the study?
Are circulating betatrophin levels increased in women with gestational diabetes mellitus compared to healthy pregnant controls?
Population
148 pregnant women, comprising 74 women with gestational diabetes mellitus and 74 healthy and gestational…
Design
Case-control
Follow-up
postpartum
Authors
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Betatrophin elevation is associated with GDM; hypothesis-generating and should not yet change practice.
Case-Control (n=148)
Are circulating betatrophin levels increased in women with gestational diabetes mellitus compared to healthy pregnant controls?
Absolute Event Rate: 1.79% vs 1.58%
p-value: p=0.002
Circulating betatrophin levels are significantly elevated in women with gestational diabetes mellitus during pregnancy and decrease postpartum.
Ebert et al. (2015) conducted a case-control in Gestational diabetes mellitus (n=148). Gestational diabetes mellitus vs. Healthy pregnant controls was evaluated on Serum betatrophin levels (μg/l) (p=0.002). Women with gestational diabetes mellitus had significantly higher median serum betatrophin levels compared to healthy pregnant controls (1.79 vs 1.58 μg/l; P=0.002).
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