Key result
Circulating betatrophin concentrations were significantly higher in women with gestational diabetes mellitus compared to pregnant women with normal glucose tolerance (29.3 vs. 18.1 ng/ml, p<0.001).
Population
50 women, including 21 pregnant women with gestational diabetes mellitus, 19 pregnant body mass…
Design
Cross-sectional
Authors
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Betatrophin elevation in GDM should not change practice; leaves open its link to lipids over glucose homeostasis.
Cross-Sectional (n=50)
No
Absolute Event Rate: 29.3% vs 18.1%
p-value: p=<0.001
Circulating betatrophin concentrations are dramatically increased in pregnancy and further elevated in gestational diabetes mellitus, correlating with lipid parameters rather than glucose homeostasis.
Trebotic et al. (2015) conducted a cross-sectional in Gestational Diabetes Mellitus (n=50). Gestational Diabetes Mellitus vs. Normal glucose tolerance in pregnancy was evaluated on Circulating betatrophin concentrations (p=<0.001). Circulating betatrophin concentrations were significantly higher in women with gestational diabetes mellitus compared to pregnant women with normal glucose tolerance (29.3 vs. 18.1 ng/ml, p<0.001).
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