Key result
APC resistance was not associated with myocardial infarction, with a similar prevalence observed in non-anticoagulated MI survivors and controls (2.2% vs 2.0%).
Why the study?
Is APC resistance associated with myocardial infarction?
Population
134 non-anticoagulated survivors of myocardial infarction and 100 controls of similar age and sex distribution
Comparison
APC resistance vs Controls without myocardial infarction
Design
Case-control
Authors
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No support for APC resistance testing in MI evaluation; leaves open its role in venous thromboembolism.
Case-Control (n=234)
Is APC resistance associated with myocardial infarction?
Absolute Event Rate: 2.2% vs 2%
APC resistance is not associated with myocardial infarction, suggesting it is not a significant risk factor for arterial thromboembolic disease.
Biasiutti et al. (1995) conducted a case-control in Myocardial infarction (n=234). APC resistance vs. Controls was evaluated on Prevalence of APC resistance. APC resistance was not associated with myocardial infarction, with a similar prevalence observed in non-anticoagulated MI survivors and controls (2.2% vs 2.0%).
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