Key result
High Ang-2 levels were cross-sectionally associated with metabolic syndrome (OR 1.78) compared to low levels, but not with incident metabolic syndrome during follow-up.
Why the study?
Are high levels of Ang-2 and sTie-2 associated with prevalent or incident metabolic syndrome in a population-based sample?
Population
3,205 individuals from the population-based Study of Health in Pomerania for cross-sectional analysis, and…
Comparison
High levels of Ang-2 and sTie-2 (90th percentile) vs Low levels of Ang-2 and sTie-2 (10th percentile)
Design
Cohort
Authors
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Ang-2 links to prevalent but not incident metabolic syndrome; leaves open its causal role in cardiometabolic pathogenesis.
Observational (n=3,205)
Are high levels of Ang-2 and sTie-2 associated with prevalent or incident metabolic syndrome in a population-based sample?
Odds Ratio: 1.78
Ang-2 and sTie-2 levels are cross-sectionally associated with metabolic syndrome but do not predict incident metabolic syndrome over time.
Lorbeer et al. (2016) conducted an observational in Metabolic syndrome (n=3,205). High Ang-2 levels (90th percentile) vs. Low Ang-2 levels (10th percentile) was evaluated on Prevalence of metabolic syndrome (OR 1.78). High Ang-2 levels were cross-sectionally associated with metabolic syndrome (OR 1.78) compared to low levels, but not with incident metabolic syndrome during follow-up.
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