Key result
Sodium nitroprusside infusion in patients with normal left ventricular function increased mean coronary sinus flow from 168 ml/min to 187 ml/min and reduced myocardial oxygen extraction.
Why the study?
Does sodium nitroprusside alone and in combination with phenylephrine affect coronary dynamics in patients with normal left ventricular function?
Population
10 patients with normal left ventricular function undergoing cardiac catheterisation.
Comparison
Sodium nitroprusside infusion alone and in… vs Baseline measurements prior to infusion.
Design
Other
Authors
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May enhance coronary flow assessment in normal LV function; leaves open effects in impaired hearts or with phenylephrine.
Does sodium nitroprusside alone and in combination with phenylephrine affect coronary dynamics in patients with normal left ventricular function?
Absolute Event Rate: 187% vs 168%
Sodium nitroprusside infusion alters coronary dynamics by increasing coronary sinus flow and reducing myocardial oxygen extraction in patients with normal left ventricular function.
Stephens et al. (1979) studied Normal left ventricular function (n=10). Sodium nitroprusside vs. Baseline was evaluated on Mean coronary sinus flow. Sodium nitroprusside infusion in patients with normal left ventricular function increased mean coronary sinus flow from 168 ml/min to 187 ml/min and reduced myocardial oxygen extraction.
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