Key result
ACE genotype had no significant effect on renal survival (time to end-stage renal disease) in patients with type 2 diabetes mellitus and diabetic nephropathy.
Why the study?
Does ACE genotype affect renal survival or the risk of diabetes complications in black patients with diabetic nephropathy?
Cohort (n=54)
Does ACE genotype affect renal survival or the risk of diabetes complications in black patients with diabetic nephropathy?
p-value: p=not significant
In black patients with diabetic nephropathy, ACE genotype does not significantly impact renal survival, though the DD genotype is associated with fewer traditional risk factors for diabetes.
No takes yet. Share an insight, caveat, or question.
ACE genotyping should not guide renal prognosis in black patients with diabetic nephropathy; leaves open links to other complications.
Crook et al. (2003) conducted a cohort in Type 2 diabetes mellitus and diabetic nephropathy (n=54). ACE genotype (I/D polymorphism) vs. Different ACE genotypes (II, ID, DD) was evaluated on Time to end-stage renal disease (ESRD) from first clinic visit (p=not significant). ACE genotype had no significant effect on renal survival (time to end-stage renal disease) in patients with type 2 diabetes mellitus and diabetic nephropathy.
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