Key result
A ~3-fold higher SAECG QRS area ratio is associated with acute cardiac allograft rejection.
Why the study?
Does frequency domain analysis of signal-averaged electrocardiograms identify acute cardiac allograft rejection in transplanted patients?
Observational (n=41)
Does frequency domain analysis of signal-averaged electrocardiograms identify acute cardiac allograft rejection in transplanted patients?
Absolute Event Rate: 203% vs 66%
p-value: p=0.0007
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Frequency domain analysis of signal-averaged ECGs may serve as a useful noninvasive marker for detecting acute cardiac allograft rejection.
Valentino et al. (1992) conducted an observational in Cardiac allograft rejection (n=41). Signal-averaged electrocardiogram with frequency domain analysis via fast Fourier transform vs. Patients without acute allograft rejection was evaluated on High-frequency components of the QRS complex (QRS area ratio) (p=0.0007). Signal-averaged electrocardiograms analyzed via fast Fourier transform demonstrated a significantly higher QRS area ratio in patients with acute cardiac allograft rejection (203 vs 66, P=0.0007).
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