Why the study?
To track changes in anticoagulation and fibrinolysis indicators across different pregnancy periods and establish trimester-specific reference intervals in healthy pregnant women.
Population
200 healthy pregnant women registered in Peking University First Hospital
Comparison
Non-pregnant group vs first, second, and third trimester groups
Design
Prospective observational cohort study
Key result
Pregnancy significantly altered thirteen anticoagulant and fibrinolytic indicators across trimesters compared to non-pregnant women, necessitating trimester-specific reference intervals.
Authors
Loading...
Supports trimester-specific coagulation reference intervals in pregnancy; leaves open whether adoption improves maternal outcomes.
Observational (n=200)
No
This study establishes trimester-specific reference intervals for 13 anticoagulant and fibrinolytic indicators in healthy pregnant women in Beijing, China, highlighting the need for pregnancy-specific reference ranges.
Miao et al. (2025) conducted an observational in Healthy pregnancy (n=200). Pregnancy vs. Non-pregnant women was evaluated on Anticoagulation and fibrinolysis indicators. Pregnancy significantly altered thirteen anticoagulant and fibrinolytic indicators across trimesters compared to non-pregnant women, necessitating trimester-specific reference intervals.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: