Key result
Reverse remodeling after heart valve replacement depends on fibrosis severity and requires comprehensive multimodal assessment.
Why the study?
Acquired heart valve disorders require valve replacement, but the extent and mechanisms of myocardial remodeling and its reversal postoperatively remain to be comprehensively evaluated.
This review highlights the importance of assessing myocardial fibrosis and matrix metalloproteinases to predict reverse myocardial remodeling after heart valve replacement.
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Kuzmina et al. (2017) conducted a review in Acquired heart valve diseases. Heart valve replacement was evaluated. Reverse myocardial remodeling after heart valve replacement depends on the degree of myocardial fibrosis and requires comprehensive evaluation using clinical, instrumental, and humoral markers.
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