Key result
Isolated rat heart intramuscular pH fluctuates during contraction-relaxation cycles independent of mechanical activity.
Population
Isolated perfused rat hearts
Design
Experimental study measuring intramuscular pH oscillations
Authors
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No immediate clinical implications for myocardial pH management; leaves open in vivo validation and relevance to human cardiac physiology.
Dhalla et al. (1973) studied this question. Isolated perfused rat heart model was evaluated on Intramuscular pH. Intramuscular pH of the isolated perfused rat heart fluctuated between 7.11 and 7.14 during each contraction-relaxation cycle, independent of mechanical activity.
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