Supplementary Figure S38 from Single-cell eQTL Mapping Reveals Cell Subtype–specific Genetic Control and Mechanism in Malignant Transformation of Colorectal Cancer

Can Chen; Yimin Cai; Wenlong Hu; Kai Tan; Zequn Lu; Xuanyu Zhu; Ziying Liu; Chunyi He; Guangping Xu; Ruizhe Zhang; Caibo Ning; Shuheng Ruan; Jiayan Gao; Xiaojun Yang; Yongchang Wei; Xu Zhu; Xiangpan Li; Faxi Wang; Fubing Wang; Jiaoyuan Li; Meng Jin; Bin Li; Ying Zhu; Jianbo Tian; Xiaoping Miao

doi:10.1158/2159-8290.29819595

Key Points

Integration of single-cell eqtl data reveals genetic control in colorectal cancer subtypes.
Expression levels of EKL1 and LGALS9 in CRC cell lines are quantified in various contexts.
Fibroblast-specific expression of SLC1A5 offers insights into tumor microenvironment interactions.
Understanding genetic control mechanisms may lead to targeted therapies for malignant transformation in colorectal cancer.

Implication

Supplementary figure highlights genetic control and expression levels in malignant transformation of colorectal cancer cells, indicating subtype specificity.

Abstract

Supplementary Figure 38 shows the expression level of EKL1 and LGALS9 in CRC cell lines and SLC1A5 in fibroblasts.

Discussion

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Cite This Study

Chen et al. (2025) studied this question.

synapsesocial.com/papers/689a0f86e6551bb0af8d0978 https://doi.org/10.1158/2159-8290.29819595

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Supplementary Figure S38 from Single-cell eQTL Mapping Reveals Cell Subtype–specific Genetic Control and Mechanism in Malignant Transformation of Colorectal Cancer

Key Points

Implication

Abstract

Discussion

Cite This Study

Supplementary Figure S38 from Single-cell eQTL Mapping Reveals Cell Subtype–specific Genetic Control and Mechanism in Malignant Transformation of Colorectal Cancer

Key Points

Implication

Abstract

Discussion

Cite This Study

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