Profiling gut microbiome reveals dysbiosis and altered intestinal integrity in Eμ-TCL1 mice, suggesting disease impact.
Differential expression of markers pertaining to intestinal integrity and inflammation in WT B6 and Eμ-TCL1 mice. ELISA was used to assess the concentration of tight junction markers in plasma of 12-month-old WT B6 and Eμ-TCL1 mice: CLDN2 (A), CLDN3 (B), zonulin (C), and sCD14 (D). Asterisks denote significance between WT B6 and Eμ-TCL1 mice (**, P < 0.01; ***, P < 0.001). Unpaired Welch t test was applied for testing.
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Skupa et al. (2025) studied this question.
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