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August 15, 2025Open Access

Supplementary Figure S7 from Gut Microbiome Profiling in Eμ-TCL1 Mice Reveals Intestinal Changes and a Dysbiotic Signature Specific to Chronic Lymphocytic Leukemia

Sydney A. Skupa Kathryn Cooper Audrey L. Smith Erin M. Drengler Alexandria P. Eiken Elizabeth Schmitz Grace M. Waldron Grinu Mathew Mark Primeaux Punita Dhawan Geoffrey A. Talmon Christopher R. D’Angelo Dalia El-Gamal

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Key Points

Leukemic mice receiving antibiotics showed significant dysbiotic signature compared to those receiving water.
Relative abundance analysis revealed distinct gut microbiome profiles in both antibiotic and water-receiving leukemic mice.
Observational data from Eμ-TCL1 mice highlights how antibiotic treatment influences gut microbiota diversity.
Findings suggest that gut health may play a role in chronic lymphocytic leukemia progression and treatment outcomes.

Implication

Analysis shows distinct dysbiotic signature in leukemic mice receiving antibiotics, suggesting gut health impact.

Abstract

Figure S7. Relative abundance of microbiota in antibiotic-receiving leukemic mice vs. water-receiving leukemic mice.

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Cite This Study

Skupa et al. (2025) studied this question.

synapsesocial.com/papers/68af56faad7bf08b1eadd271 https://doi.org/10.1158/2767-9764.29917524

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Figure S6 from Gut Microbiome Profiling in Eμ-TCL1 Mice Reveals Intestinal Changes and a Dysbiotic Signature Specific to Chronic Lymphocytic Leukemia2025
2Supplementary Figure S2 from Gut Microbiome Profiling in Eμ-TCL1 Mice Reveals Intestinal Changes and a Dysbiotic Signature Specific to Chronic Lymphocytic Leukemia2025
3Supplementary Figure S5 from Gut Microbiome Profiling in Eμ-TCL1 Mice Reveals Intestinal Changes and a Dysbiotic Signature Specific to Chronic Lymphocytic Leukemia2025
4Supplementary Figure S1 from Gut Microbiome Profiling in Eμ-TCL1 Mice Reveals Intestinal Changes and a Dysbiotic Signature Specific to Chronic Lymphocytic Leukemia2025
5Supplementary Figure S3 from Gut Microbiome Profiling in Eμ-TCL1 Mice Reveals Intestinal Changes and a Dysbiotic Signature Specific to Chronic Lymphocytic Leukemia2025