Compositional analysis reveals dysbiotic signatures and specific microbial pathways in antibiotic-treated leukemic mice, suggesting potential impacts on disease progression.
Compositional analysis of microbial communities following antibiotic ablation. A, LEfSe analysis demonstrating enrichment of specific bacterial taxa at the phylum level in antibiotic-receiving (Abx) leukemic mice and water-receiving (water) leukemic mice at 3 weeks after engraftment. B, Predicted microbial function pathways at the phylum level in antibiotic-receiving leukemic mice and water-receiving mice at 3 weeks after engraftment. LDA, linear discriminant analysis.
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Skupa et al. (2025) studied this question.
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