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September 10, 2025European Journal of Translational MyologyOpen Access

Effectiveness of deep brain stimulation in alleviating treatment-resistant schizophrenia: a systematic review

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Authors

MKMohsen Khosravi

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Overview

Systematic review evaluates deep brain stimulation's effectiveness in treatment-resistant schizophrenia, suggesting its potential role in psychiatric care.

Key Points

  • Deep brain stimulation led to symptomatic improvements in about 30% of patients with treatment-resistant schizophrenia.
  • Four eligible studies were analyzed, highlighting targeted interventions in specific brain regions like the nucleus accumbens.
  • This systematic review utilized PRISMA 2020 guidelines to ensure comprehensive literature research and selection criteria.
  • Though there were ten adverse events reported, the findings suggest that deep brain stimulation may enhance treatment options in clinical settings.

Cite This Study

Mohsen Khosravi (2025) studied this question.

synapsesocial.com/papers/68c1924e9b7b07f3a0616a99https://doi.org/10.4081/ejtm.2025.14206
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Deep Brain Stimulation in Treatment-Resistant Psychiatric Disorders: Efficacy, Safety, and Future Directions2025
  2. 2Deep brain stimulation for clozapine-resistant schizophrenia: a systematic review of target-specific outcomes and stereotactic technical considerations.2026
  3. 3Deep Brain Stimulation Is Beneficial for Treatment-Resistant Depression: A Systematic Review and Meta-Analysis of Clinical Trials and Long-Term Follow-Ups2025
  4. 4Deep brain stimulation beneficial for treatment-resistant depression: A systematic review and meta-analysis of clinical trials and long-term follow-up studies2026
  5. 5Deep brain stimulation is beneficial for treatment-resistant depression: A systematic review and meta–analysis of clinical trials and long-term follow-ups2025