Key result
Paradise ultrasound catheter reduces SBP by ~6 mmHg versus sham controls.
Why the study?
Renal denervation represents a new dimension to hypertension treatment with devices seeking FDA approval, spurring interest into its efficacy, safety, and underlying mechanisms.
Does renal denervation reduce systolic blood pressure in individuals with hypertension?
Design
Review
Authors
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Supports Paradise renal denervation for SBP reduction; leaves open standardization across devices amid mixed evidence.
Does renal denervation reduce systolic blood pressure in individuals with hypertension?
Renal denervation demonstrates a robust antihypertensive effect, particularly when antihypertensive medications are withdrawn, though results vary across different trials and devices.
Drawz et al. (2023) studied this question. The ultrasound Paradise Catheter system achieved a significant 6.3 mmHg reduction in SBP compared to sham controls, highlighting its antihypertensive efficacy.
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