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June 1, 2009European Journal of Cardiovascular Prevention & RehabilitationOpen Access

Relationship between plasma antioxidant concentrations and carotid intima-media thickness: the Asymptomatic Carotid Atherosclerotic Disease In Manfredonia Study

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Why the study?

Is there a relationship between plasma antioxidant concentrations and carotid intima-media thickness in asymptomatic carotid atherosclerotic disease?

Population

Patients with asymptomatic carotid atherosclerotic disease

Design

Other

Authors

GRGraziano RiccioniNDNicolantonio D’OrazioNPNicola Palumbo

Discussion

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Overview

Supports antioxidant focus in prevention; cross-sectional data leaves causal role open for prospective trials.

Structured PICO

Is there a relationship between plasma antioxidant concentrations and carotid intima-media thickness in asymptomatic carotid atherosclerotic disease?

P
Population
Patients with asymptomatic carotid atherosclerotic disease
I
Intervention
Plasma antioxidant concentrations
O
Outcome
Carotid intima-media thicknesssurrogate

Adequate intake of antioxidant micronutrients, along with optimal control of traditional risk factors, is highlighted as key for the prevention of atherosclerotic disease.

Cite This Study

Riccioni et al. (2009) studied this question.

synapsesocial.com/papers/69d56eef75589c71d767d7d4https://doi.org/10.1097/hjr.0b013e328325d807
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Progression of Carotid Intima-Media Thickness and Plasma Antioxidants: The Los Angeles Atherosclerosis Study2003 · 132 citations
  2. 2Common Carotid Intima-Media Thickness Predicts Occurrence of Carotid Atherosclerotic Plaques2000 · 237 citations
  3. 3Plasma Vitamins E and A Inversely Correlated to Mortality from Ischemic Heart Disease in Cross‐Cultural Epidemiology1989 · 240 citations
  4. 4Circulating Oxidized LDL Is a Useful Marker for Identifying Patients With Coronary Artery Disease2001 · 532 citations
  5. 5Mortality Associated With Low Plasma Concentration of Beta Carotene and the Effect of Oral Supplementation1996 · 196 citations