Key result
Dobutamine-tagged MRI in severe CAD showed inotropic reserve was more frequently present in mismatch viable regions (52%) than in normal, match viable, and infarcted regions (~40%, P<0.05).
Observational (n=18)
p-value: p=<0.05
In severe CAD, inotropic reserve assessed by dobutamine-tagged MRI does not relate to resting perfusion but is inversely related to resting contractile performance, except in hibernating myocardium.
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Preserved inotropic reserve in mismatch regions on dobutamine-tagged MRI warrants further study in severe CAD; leaves open incremental clinical utility beyond PET.
Mazzadi et al. (2004) conducted an observational in Severe coronary artery disease (CAD) (n=18). Low-dose dobutamine during tagged MRI vs. Resting state was evaluated on Relationship between PET patterns of perfusion/glucose uptake and tagged MRI values of midmyocardial strains (Ecc) (p=<0.05). Dobutamine-tagged MRI in severe CAD showed inotropic reserve was more frequently present in mismatch viable regions (52%) than in normal, match viable, and infarcted regions (~40%, P<0.05).
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