Key result
Rapid cardiac pacing in rabbits induced reversible LV dysfunction and adrenergic changes without permanent structural neuronal damage within the first 8 weeks.
Authors
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Early pacing-induced LV dysfunction appears reversible without neuronal damage in rabbits; leaves open translation to human tachyarrhythmia mechanisms.
Kawai et al. (2000) studied Congestive heart failure. Cardiac pacing was evaluated on Temporal sequence of cardiac adrenergic nerve terminal changes and beta-adrenoceptor density. Rapid cardiac pacing in rabbits induced reversible LV dysfunction and adrenergic changes without permanent structural neuronal damage within the first 8 weeks.
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