Serum levels of advanced glycation end products are associated with left ventricular diastolic function in patients with type 1 diabetes.

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Why the study?

Are serum levels of advanced glycation end products associated with left ventricular diastolic function in patients with type 1 diabetes?

Population

52 patients with type 1 diabetes, mean age 40 +/- 13 years, diabetes duration 17 +/- 13 years, and HbA1c 8.3…

Design

Cross-sectional

Authors

Discussion

Serum AGEs may contribute to diastolic dysfunction in type 1 diabetes; leaves open causal role and need for prospective trials.

Are serum levels of advanced glycation end products associated with left ventricular diastolic function in patients with type 1 diabetes?

Population

52 patients with type 1 diabetes, mean age 40 +/- 13 years, diabetes duration 17 +/- 13 years, and HbA1c 8.3 +/- 1.1%.

Outcome

Left ventricular diastolic and systolic function assessed by M-mode and Doppler echocardiographysurrogate

Berg et al. (1999) studied this question.

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