Key result
Intravascular ultrasound correctly identified plaque in 83% of patients and correlated well with histological measurements for determining luminal area (r = 0.89).
Why the study?
Does intravascular ultrasound accurately characterize the arterial lumen and atherosclerotic plaque in human cerebral arteries compared to histology?
Population
22 arterial segments obtained at autopsy from 6 patients
Comparison
Intravascular ultrasound imaging using a 30-MHz… vs Histological examination
Design
Preclinical
Authors
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Supports exploratory IVUS use in cerebral arteries; leaves open clinical validation in prospective human studies.
Observational (n=6)
Does intravascular ultrasound accurately characterize the arterial lumen and atherosclerotic plaque in human cerebral arteries compared to histology?
Effect estimate: r = 0.89
Intravascular ultrasound accurately characterizes the arterial lumen and atherosclerotic plaque in human cerebral arteries in vitro, correlating well with histology.
Ravalli et al. (1996) conducted an observational in Cerebral atherosclerosis (n=6). Intravascular ultrasound imaging vs. Histological examination was evaluated on Correlation between luminal area measurements determined histologically and by intravascular ultrasound (r = 0.89). Intravascular ultrasound correctly identified plaque in 83% of patients and correlated well with histological measurements for determining luminal area (r = 0.89).
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