Why the study?
Does intravascular ultrasound imaging accurately measure arterial wall thickness compared to histology in human atherosclerotic arteries?
Population
14 segments of human atherosclerotic arteries (in vitro)
Comparison
Prototype intravascular ultrasound imaging… vs Histologic sections at the same levels
Design
Preclinical
Authors
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Supports IVUS validation in animal models; leaves open translation to human atherosclerotic arteries.
Does intravascular ultrasound imaging accurately measure arterial wall thickness compared to histology in human atherosclerotic arteries?
Intravascular ultrasound with a 20 MHz transducer provides accurate measurements of microanatomic arterial dimensions and atheromatous involvement compared to histology.
Mallery et al. (1990) studied this question.
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