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A lumped parameter model demonstrates that coronary sinus occlusion can renew about two thirds of the blood stored in the microcirculation per cardiac cycle.
The coronary vasculature of the Icft ventricle of thc heart is represented in a lumped parameter modcl, consisting of an arterial, a microcirculatory and a venous compartment. The differential equations are solved for the boundary conditions of coronary sinus interventions both during normal arterial perfusion and coronary artery obsuuction. representation of the venous compartment, in particular of iB volume dependent compliance [9]. In this scnsc, thc prcscnt modcl is an advantagc as compared to previous approaches [lo]. Based on adcquate reproduction of venous hemodynamics, we found for coronary sinus occlusion in thc undiscased statc that oscillating flow between microcirculatory and venous compartment is able to renew in each cardiac cyclcabout two thirds of the blood stored in the microcirculation [91.
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Schreiner et al. (2005) studied this question.
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