Why the study?
Does etomoxir improve myocardial function and modify left ventricular hypertrophy in rats with prolonged pressure overload?
Does etomoxir improve myocardial function and modify left ventricular hypertrophy in rats with prolonged pressure overload?
In a rat model of pressure overload, chronic etomoxir treatment improved myocardial function and delayed dilative remodeling of hypertrophied left ventricles.
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Should not change clinical practice in hypertrophy; leaves open translation of etomoxir effects to human pressure-overload heart failure.
Turčáni et al. (1999) studied this question.