Key result
Cholecalciferol linked to ~60% lower prevalence of EDV impairments in early postmenopausal women.
Why the study?
The study was conducted to assess the effect of cholecalciferol supplementation on endothelial function in premenopausal and early postmenopausal women with arterial hypertension.
Does cholecalciferol supplementation improve endothelial function in women with arterial hypertension and vitamin D deficiency?
Cohort (n=102)
Does cholecalciferol supplementation improve endothelial function in women with arterial hypertension and vitamin D deficiency?
Absolute Event Rate: 14.3% vs 35.5%
p-value: p=0.05
Supplementation with cholecalciferol 2000 IU/day for 3 months improves endothelial function in women with arterial hypertension and vitamin D deficiency, particularly in the early postmenopausal period.
Authors
No takes yet. Share an insight, caveat, or question.
May support endothelial benefits of cholecalciferol repletion in early postmenopausal hypertensive women; hypothesis-generating and requires randomized confirmation.
Л В Кежун (2026) conducted a cohort in Arterial hypertension (n=102). Cholecalciferol vs. No cholecalciferol was evaluated on Prevalence of endothelium-dependent vasodilation (EDV) impairments in early postmenopausal women (p=0.05). Cholecalciferol supplementation of 2000 IU/day for 3 months decreased the prevalence of endothelium-dependent vasodilation impairments in early postmenopausal women (14.3% vs 35.5%, p=0.05).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: