Why the study?
Does the combination of varying doses of propranolol and hydrochlorothiazide 25 mg daily improve blood pressure control in patients with mild and moderate hypertension?
Does the combination of varying doses of propranolol and hydrochlorothiazide 25 mg daily improve blood pressure control in patients with mild and moderate hypertension?
The combination of propranolol and hydrochlorothiazide provided good blood pressure control in 90% of patients with mild to moderate hypertension without significant side effects.
Answers are grounded in this paper and cite their sources.
Hypothesis-generating for propranolol-hydrochlorothiazide in mild-moderate hypertension; does not support practice change without randomized evidence.
Twenty patients with mild and moderate hypertension were treated with varying doses of propranolol along with hydrochlorothiazide 25 mg daily. In eighteen patients ( 90%) the blood pressure control was good. Bronchospasm, congestive heart failure, significant postural hypotension and other bothersome side-effects were not observed. Propranolol has the merit of causing a slow reduction in blood pressure without troublesome side-effects.
No takes yet. Share an insight, caveat, or question.
Nigam et al. (1973) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: