Why the study?
Does visceral smooth muscle from spontaneously hypertensive rats show altered reactivity compared to normotensive rats?
Does visceral smooth muscle from spontaneously hypertensive rats show altered reactivity compared to normotensive rats?
Visceral smooth muscle in spontaneously hypertensive rats exhibits altered reactivity similar to arterial smooth muscle, suggesting the cellular modification is a primary defect rather than an adaptation to high blood pressure.
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Altered visceral smooth muscle reactivity in SHR models suggests primary cellular defect; extends vascular findings but leaves human translation open.
Altman et al. (1977) studied this question.
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