August 10, 2009Congestive Heart Failure

CA125 levels >35 U/mL were predictive of 40-month all-cause mortality (adjusted hazard ratio, 2.53; 95% CI, 1.40-4.59; P=.002).

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Why the study?

Does elevated serum CA125 predict long-term mortality in African American patients with acute decompensated heart failure?

Population

172 consecutive African American patients admitted with a clinical diagnosis of acute decompensated heart…

Comparison

Elevated serum carbohydrate antigen 125 levels… vs Lower serum CA125 levels (≤35 U/mL)

Design

Cohort

Follow-up

median 40 months

Authors

IMIbrahim N. Mansour SNSirikarn Napan MAM. Tarek Alahdab

Discussion

Member takes

Overview

May aid prognostication in African American ADHF patients; extends evidence to this group but remains hypothesis-generating.

Structured PICO

Does elevated serum CA125 predict long-term mortality in African American patients with acute decompensated heart failure?

Population

172 consecutive African American patients admitted with a clinical diagnosis of acute decompensated heart failure, mean age 55.8 years, 61.1% men.

Intervention

Elevated serum carbohydrate antigen 125 (CA125) levels (>35 U/mL) measured within 48+/-12 hours of presentation

Comparator

Lower serum CA125 levels (≤35 U/mL)

Outcome

40-month all-cause mortalityhard clinical

Elevated serum CA125 (>35 U/mL) is a strong, independent predictor of long-term all-cause mortality in African American patients admitted with acute decompensated heart failure.

Cite This Study

Mansour et al. (2009) studied this question.

synapsesocial.com/papers/6a73c2660e7fa2a8810dd24e https://doi.org/10.1111/j.1751-7133.2009.00110.x

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August 10, 2009Congestive Heart Failure

CA125 levels >35 U/mL were predictive of 40-month all-cause mortality (adjusted hazard ratio, 2.53; 95% CI, 1.40-4.59; P=.002).

View Full Paper

Ask AI

Bookmark

Why the study?

Does elevated serum CA125 predict long-term mortality in African American patients with acute decompensated heart failure?

Population

172 consecutive African American patients admitted with a clinical diagnosis of acute decompensated heart…

Comparison

Elevated serum carbohydrate antigen 125 levels… vs Lower serum CA125 levels (≤35 U/mL)

Design

Cohort

Follow-up

median 40 months

Authors

IMIbrahim N. Mansour SNSirikarn Napan MAM. Tarek Alahdab

Discussion

Member takes

Overview

May aid prognostication in African American ADHF patients; extends evidence to this group but remains hypothesis-generating.

Structured PICO

Does elevated serum CA125 predict long-term mortality in African American patients with acute decompensated heart failure?

Population

172 consecutive African American patients admitted with a clinical diagnosis of acute decompensated heart failure, mean age 55.8 years, 61.1% men.

Intervention

Elevated serum carbohydrate antigen 125 (CA125) levels (>35 U/mL) measured within 48+/-12 hours of presentation

Comparator

Lower serum CA125 levels (≤35 U/mL)

Outcome

40-month all-cause mortalityhard clinical

Elevated serum CA125 (>35 U/mL) is a strong, independent predictor of long-term all-cause mortality in African American patients admitted with acute decompensated heart failure.

Cite This Study

Mansour et al. (2009) studied this question.

synapsesocial.com/papers/6a73c2660e7fa2a8810dd24e https://doi.org/10.1111/j.1751-7133.2009.00110.x

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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