Why the study?
Does preoperative pregabalin improve postoperative pain relief compared to gabapentin in patients undergoing abdominal hysterectomy?
Population
60 patients undergoing abdominal open hysterectomy under spinal anaesthesia
Comparison
Pregabalin 300 mg orally one hour before spinal… vs Gabapentin 900 mg orally one hour before spinal…
Design
RCT, randomised
Follow-up
postoperative phase
Authors
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May support gabapentinoids for post-hysterectomy pain; leaves open optimal dosing and efficacy versus standard care.
Does preoperative pregabalin improve postoperative pain relief compared to gabapentin in patients undergoing abdominal hysterectomy?
Pre-emptive pregabalin (300 mg) provides superior postoperative analgesia compared to gabapentin (900 mg) in patients undergoing abdominal hysterectomy.
Gayathri et al. (2017) studied this question.
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