Why the study?
Does modulation of nitric oxide with L-NAME or SNP alter whole body oxygen consumption in anesthetized dogs?
Does modulation of nitric oxide with L-NAME or SNP alter whole body oxygen consumption in anesthetized dogs?
Basally released endogenous NO has a tonic systemic vasodilator effect but does not modulate whole-body oxygen consumption in anesthetized dogs.
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NO modulation does not alter VO2 in anesthetized dogs; hypothesis-generating and should not change practice.
Crystal et al. (1999) studied this question.
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