Population
Encephalomyocarditis virus (EMCV) RNA (in vitro translation models)
Comparison
Deletion mutations within the 5' noncoding… vs Wild-type or other deletion mutants
Design
Preclinical
Authors
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Maps EMCV IRES domains for mutagenesis studies; leaves open relevance to mammalian translation or antiviral strategies.
Identifies specific structural domains within the EMCV RNA 5' noncoding region that are essential for internal ribosome entry site (IRES)-mediated translation initiation.
Evstafieva et al. (1991) studied this question.
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