Population
Beagle dogs, anaesthetized with morphine and chloralose
Design
Preclinical
Authors
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Hypothesis-generating for pre-hypotensive baroreflex responses; human studies required before any clinical consideration.
Aortic baroreceptor discharge is reduced during non-hypotensive haemorrhage via aortic smooth muscle constriction and compensatory mechanisms, allowing response to hypovolaemia before hypotension occurs.
Hartikainen et al. (1990) studied this question.
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