Why the study?
Does dopamine infusion reduce the aldosterone response to upright posture in normal men?
Population
12 normal men eating an ad libitum sodium diet
Comparison
Dopamine infusion of 4.0 micrograms/kg x min vs 5% dextrose vehicle infusion
Design
Other
Follow-up
4 hours
Authors
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Dopamine may modulate postural aldosterone release in healthy men; leaves open relevance to hypertension or clinical practice.
Does dopamine infusion reduce the aldosterone response to upright posture in normal men?
Dopamine infusion significantly inhibits the aldosterone response to upright posture in normal men without affecting plasma renin activity, aldosterone-stimulating factor, or cortisol.
Malchoff et al. (1986) studied this question.
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