Population
In situ working heart-brain stem preparation (WHBP) model
Comparison
Bilateral microinjections of kynurenic acid into… vs Baseline (before microinjections)
Design
Preclinical
Authors
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Extends animal evidence for NTS glutamatergic control of chemoreflex; leaves open translation to human cardiorespiratory physiology.
Glutamatergic neurotransmission in the iNTS and cNTS plays a tonic role on baseline respiratory rhythm and is essential for expiratory-related sympathoexcitation during chemoreflex activation.
Costa‐Silva et al. (2010) studied this question.
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