Population
Hepatitis C virus (HCV) 5'-UTR genotypes 1, 2, and 3 evaluated in a bicistronic expression system
Comparison
HCV genotype 3 5'-UTR and site-directed… vs HCV genotypes 1 and 2 5'-UTR
Design
Preclinical
Authors
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May explain HCV genotype differences in interferon response; animal data leave open human translation.
Differences in translational initiation efficiency among HCV genotypes may explain variations in viral infection behavior and response to interferon therapy.
Buratti et al. (1997) studied this question.
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