Why the study?
Does early dose titration of amlodipine improve the antihypertensive effect in patients with mild to moderate hypertension?
Does early dose titration of amlodipine improve the antihypertensive effect in patients with mild to moderate hypertension?
Early dose titration of amlodipine before six weeks provides no additional antihypertensive advantage compared to maintaining a 5 mg daily dose in patients with mild to moderate hypertension.
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Early amlodipine titration before 6 weeks adds no benefit; confirms fixed 5 mg dosing suffices in mild-moderate hypertension.
Hayduk et al. (1999) studied this question.
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