In a canine model, the splanchnic circulation is the primary contributor to increased vascular resistance in hypertension.
Hypothesis-generating for regional vasomotor control in hypertension; leaves open translation to human disease or therapy.
A new method for estimating vasomotor tone in a local circulation by means of the asystolic arterial pressure gradient was applied to the renal, femoral, brachial, and mesenteric vascular beds of normal dogs and of dogs made hypertensive by various technics. The splanchnic circulation apparently contributes the greatest proportion of the increase of resistance in anesthetized hypertensive animals. The correlation of vasomotor tone with diastolic pressure was good only in the mesenteric area. Some differences in these four areas were found between renal and neurogenic hypertension.
No takes yet. Share an insight, caveat, or question.
Williams et al. (1951) studied this question.
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: