Population
Conscious Long Evans rats
Comparison
i.v. bolus injections of low doses of… vs i.v. bolus injections of low doses of…
Design
Preclinical
Authors
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Warrants no change in clinical practice; leaves open the role of cyclo-oxygenase products in endothelin-mediated haemodynamics for translational research.
This preclinical study demonstrates that cyclo-oxygenase products mediate some of the regional haemodynamic effects of endothelins and sarafotoxin-S6b in rats.
Gardiner et al. (1990) studied this question.
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