Abiotrophia defectiva can cause culture-negative infective endocarditis in children, which can be successfully managed with prolonged antibiotic therapy.
Alerts clinicians to Abiotrophia defectiva in pediatric culture-negative endocarditis; leaves open optimal therapy duration for this rare pathogen.
Abiotrophia defectiva, formerly designated as the member of nutritionally variant streptococci, is a part of normal oral flora and may be a cause of culture-negative endocarditis. We report a case of infective endocarditis caused by A. defectiva involving the mitral valve in a 12-year-old girl. She received antibiotic treatment for 8 weeks and was symptom-free 6 months after discharge. We also reviewed the pediatric cases of nutritionally variant streptococcal endocarditis published in the English literature since 1971.
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Chang et al. (2002) studied this question.
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