Why the study?
Does age affect the blood pressure sensitivity to sodium nitroprusside during hypotensive anesthesia?
Population
16 patients (young and elderly) undergoing deliberate hypotensive anesthesia
Comparison
Sodium nitroprusside (incremental dose increases) vs Young vs elderly patients (correlation with age)
Design
Cohort
Follow-up
During nitroprusside infusion
Authors
Loading...
May support lower nitroprusside dosing in elderly patients; leaves open need for prospective confirmation during hypotensive anesthesia.
Does age affect the blood pressure sensitivity to sodium nitroprusside during hypotensive anesthesia?
Elderly patients exhibit increased sensitivity to the hypotensive effects of sodium nitroprusside, requiring lower doses to achieve the same degree of hypotension as younger patients.
Wood et al. (1986) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: