Why the study?
Does human renin antiserum reduce blood pressure in normotensive marmosets?
Population
Conscious and anesthetized normotensive small new world monkeys (common marmosets)
Comparison
Antiserum against pure human kidney renin vs Teprotide
Design
Preclinical
Authors
Loading...
Renin antiserum lowers BP in normotensive primates; leaves open translation of renin inhibition to human hypertension management.
Does human renin antiserum reduce blood pressure in normotensive marmosets?
Antisera against human renin can specifically block the renin-angiotensin system and lower blood pressure in normotensive primates, with the magnitude of effect dependent on sodium balance.
Michel et al. (1984) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: