Key result
Quadripolar left ventricular leads in CRT-D systems were associated with lower inpatient heart failure hospitalization rates compared to bipolar leads (0.20 vs 0.31 per patient-year; IRR 0.62, P=0.036).
Why the study?
Does quadripolar left ventricular lead placement reduce heart failure hospitalization rates and costs compared to bipolar leads in patients receiving CRT-D?
Population
125 patients with de novo left ventricular leads implanted as part of a CRT-D system between January 2011…
Comparison
Quadripolar left ventricular leads as part of a… vs Bipolar left ventricular leads as part of a…
Design
Cohort
Follow-up
≥1-year
Authors
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Quadripolar LV leads may lower HF hospitalizations in CRT-D; hypothesis-generating, needs randomized confirmation.
Observational (n=125)
Does quadripolar left ventricular lead placement reduce heart failure hospitalization rates and costs compared to bipolar leads in patients receiving CRT-D?
Relative Risk: 0.62
Absolute Event Rate: 0.2% vs 0.31%
p-value: p=0.036
Quadripolar LV leads in CRT-D systems are associated with lower inpatient heart failure hospitalization rates and reduced healthcare costs compared to bipolar leads.
Corbisiero et al. (2016) conducted an observational in Heart failure (n=125). Quadripolar (QUAD) left ventricular leads vs. Bipolar (BIP) left ventricular leads was evaluated on Inpatient heart failure hospitalization (HFH) rate (IRR 0.62, p=0.036). Quadripolar left ventricular leads in CRT-D systems were associated with lower inpatient heart failure hospitalization rates compared to bipolar leads (0.20 vs 0.31 per patient-year; IRR 0.62, P=0.036).
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