Why the study?
Does oral verapamil prevent the progression of myocardial contractile and electrical dysfunction in cardiomyopathic Syrian hamsters?
Does oral verapamil prevent the progression of myocardial contractile and electrical dysfunction in cardiomyopathic Syrian hamsters?
Continuous calcium channel blockade with verapamil prevents the progression of myocardial contractile and electrical dysfunction in a hamster model of congestive heart failure.
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Provides preclinical support for verapamil in cardiomyopathy models; leaves open translation to human heart failure therapy.
Capasso et al. (1990) studied this question.
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