Why the study?
Does felodipine compared to enalapril improve cardiopulmonary exercise test results in patients with NYHA class III congestive heart failure due to ischaemic heart disease?
Population
20 patients with New York Heart Association class III congestive heart failure due to ischaemic heart disease
Comparison
Felodipine 10 mg b.i.d. for 16 weeks vs Enalapril 10 mg b.i.d. for 16 weeks
Design
Cohort
Follow-up
16 weeks
Authors
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Supports hemodynamic but not exercise benefits of felodipine versus enalapril in NYHA III ischemic HF; leaves open comparative outcome effects.
Does felodipine compared to enalapril improve cardiopulmonary exercise test results in patients with NYHA class III congestive heart failure due to ischaemic heart disease?
In patients with NYHA class III ischemic heart failure, enalapril improves exercise capacity (VO2max and duration), whereas felodipine primarily reduces arterial pressure and heart rate without improving exercise capacity.
Dunselman et al. (1990) studied this question.
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