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September 1, 1981Circulation ResearchOpen Access

Regulation of vascular angiotensin II receptors in the rat during altered sodium intake.

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Authors

GAG. AguileraUniversity of Iowa
Kevin Catt
Kevin CattNational Institutes of Health

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Implication

Vascular AII receptor downregulation by 40% during sodium restriction may blunt responsiveness; leaves open human translation and therapeutic targeting.

Key Points

Key points are not available for this paper at this time.

Cite This Study

Aguilera et al. (1981) studied this question.

synapsesocial.com/papers/6a882184cb36de311aaa693fhttps://doi.org/10.1161/01.res.49.3.751
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Control of aldosterone secretion during sodium restriction: Adrenal receptor regulation and increased adrenal sensitivity to angiotensin II1978 · 122 citations
  2. 2Action of Angiotensins I, II, and III on Aldosterone Production by Isolated Rat Adrenal Zona Glomerulosa Cells: Importance of Metabolism and Conversion of Peptides<i>in Vitro</i>*1980 · 18 citations
  3. 3The Effect of Angiotensin II on the Blood Pressure in Humans with Hypertensive Disease*1964 · 258 citations
  4. 4Competitive Binding Activity of Angiotensin II Analogues in an Adrenal Cortex Radioligand-Receptor Assay1975 · 33 citations
  5. 5Metabolism and Biological Activities of Angiotensin II and des-Asp1-Angiotensin II in Isolated Adrenal Glomerulosa Cells1979 · 23 citations