Why the study?
Does isoproterenol 5 micrograms IV produce a consistent, noticeable tachycardia to serve as a marker of intravenous injection in healthy, laboring women?
Population
20 healthy, laboring women (n=10 per group)
Comparison
Isoproterenol 5 micrograms IV vs Normal saline IV
Design
RCT, randomized, double-blind
Follow-up
10 minutes post-injection
Authors
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Isoproterenol 5 μg IV produces detectable maternal tachycardia; supports its evaluation as an intravascular injection marker in laboring women, pending safety data.
Does isoproterenol 5 micrograms IV produce a consistent, noticeable tachycardia to serve as a marker of intravenous injection in healthy, laboring women?
Isoproterenol 5 micrograms IV effectively produces a noticeable tachycardia in laboring women, suggesting potential utility as a marker for intravascular injection, though epidural safety requires further animal testing.
Leighton et al. (1989) studied this question.
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